Romidepsin (FK228) regulates the expression of the immune checkpoint ligand PD-L1 and suppresses cellular immune functions in colon cancer.

Cancer Immunol Immunother · 2021 · PMC7838139 · PMID 32632663

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an increasing trendno p-value reported

And compared with anti-PD-1 antibody treatment, the tumor suppression effect of the combination therapy also showed an increasing trend (Fig. 7 a).

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