highly significantP < .01
Statistical Analysis Statistical analysis was performed with the Wilcoxon rank-sum test for comparison of 2 time points and the Spearman test for correlation ( P < .05, significant; P < .01, highly significant).
Statistical Analysis Statistical analysis was performed with the Wilcoxon rank-sum test for comparison of 2 time points and the Spearman test for correlation ( P < .05, significant; P < .01, highly significant).