an increasing trendp<0.001
In a fully adjusted model, using the 36th month scores as reference, there is an increasing trend between the supplement users and non-users for the MMSE (estimate: −1.22; 95% CI: −1.78,0.67) (p<0.001), digit span (estimate: −1.11 (95% CI: −1.56,-0.66)) (p<0.001) and VRI scores (estimate value of −10.47 (95% CI: −15.41, −5.17)) (p<0.001).