A novel nasal co-loaded loratadine and sulpiride nanoemulsion with improved downregulation of TNF-α, TGF-β and IL-1 in rabbit models of ovalbumin-induced allergic rhinitis.

Drug Deliv · 2021 · PMC7850330 · PMID 33501873

Europe PMC DOI

hedged sentence

0.0001

closest p · 0.0× alpha

0.0001

boldest claim

The sentences

highly significantp < .0001actually significant

However, nasal mucosa relative mRNA expression of TNF-α, IL-1and TGF-β in the group treated with the nanoemulsion formulation, F3 (V) displayed a further and highly significant decrease relative to the positive control ( p < .0001). 4.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.