Lycorine hydrochloride induces reactive oxygen species-mediated apoptosis via the mitochondrial apoptotic pathway and the JNK signaling pathway in the oral squamous cell carcinoma HSC-3 cell line.

Oncol Lett · 2021 · PMC7856689 · PMID 33613725

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a decreasing trendno p-value reported

Increments in reactive oxygen species (ROS) may induce OSCC cell death, and a decreasing trend in ROS is observed in patients with advanced stage OSCC, suggesting that ROS may be an important potential antitumor target in OSCC therapeutic strategies.

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