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Topical vitamin C, vitamin E, and acetylcysteine as corneal wound healing agents: A comparative study.

Indian J Ophthalmol · 2020 · PMC7856962 · PMID 33229673

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a nonsignificant trendno p-value reported
The results of study by Ramaesh et al ., demonstrated that that acetylcysteine is effective at reducing matrix metalloproteinases-9 (MMP-9) secretion in human corneal epithelial cell cultures in a concentration-dependent manner (significant for 20 mmol and a nonsignificant trend for10 mmol).[ 7 ] The inhibitory properties of acetylcysteine on inflammation has been shown to act through nuclear factor-kB, which has a pivotal role in inducing the expression of multiple genes in immune and inflammatory responses.

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