Constitutive activation of integrin αvβ3 contributes to anoikis resistance of ovarian cancer cells.

Mol Oncol · 2021 · PMC7858284 · PMID 33155399

Europe PMC DOI

hedged sentence

0.0650

closest p · 1.3× alpha

0.0650

boldest claim

The sentences

close to significanceP = 0.065so close (0.05 < p ≤ 0.1)

Caspase activation as a function of the αvβ3 activation state Detection of cleaved and thus activated caspase‐3 by western blot analysis revealed in TMD‐GpA‐I transfectants a not significant ~ 3‐fold difference when compared to TMD‐αvβ3 and a ~ 4.6‐fold decreased caspase‐3 activation compared to TMD‐GpA expressers, which was close to significance ( P = 0.065).

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