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The comparison effects of intra-articular injection of Platelet Rich Plasma (PRP), Plasma Rich in Growth Factor (PRGF), Hyaluronic Acid (HA), and ozone in knee osteoarthritis; a one year randomized clinical trial.

BMC Musculoskelet Disord · 2021 · PMC7860007 · PMID 33536010

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an increasing trendno p-value reported
2 , 3 and 4 , despite lower WOMAC, VAS, and Lequesne scores were observed at 2th month post-injection in all groups, these scores showed an increasing trend after the sixth months, which reaches its peak (near to the baseline) after 12 months.

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