Improved migration and tube formation capacities along with an increasing trend in proliferative ability were observed in HAECs cultured in conditioned medium harvested from FOXO3-GE-MPCs relative to HAECs cultured in fresh MPC medium or conditioned medium harvested from WT-MPCs (Figs. 2 F and S2E–G).
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FOXO3-engineered human mesenchymal progenitor cells efficiently promote cardiac repair after myocardial infarction.
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