Barely Significant
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Impacts of COVID-19 pandemic on the wastewater pathway into surface water: A review.

Sci Total Environ · 2021 · PMC7862925 · PMID 33607440

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highly significantno p-value reported
The lack of information about the type and amount of COVID-19-related active principal and metabolites being released into sewage, arriving in the wastewater influent, or being released with the wastewater treatment plant effluent into receiving water bodies is a highly significant knowledge gap which merits further investigation because of the known and unknown biological activity of these chemicals and the potential effects these may have on aquatic species and/or human health.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.