Whereas CRT was detectable in WT cells (averaged PSM was 24.3) but undetectable in the CRT KO cells, CNX was present at an averaged abundance ratio of 0.08 in CNX KO cells, indicating that the CNX knockdown, although highly significant, was not complete.
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Calreticulin enhances the secretory trafficking of a misfolded α-1-antitrypsin.
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