A lymph node-targeted Amphiphile vaccine induces potent cellular and humoral immunity to SARS-CoV-2.

Sci Adv · 2021 · PMC7864572 · PMID 33547083

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a decreasing trendno p-value reported

While a decreasing trend was observed in the frequency of lung cytokine-producing CD8 + T cells in AMP-CpG–immunized animals, even the 1-μg dose level produced frequencies >3- or >30-fold higher than animals immunized with soluble CpG or alum, respectively.

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