Sperm DNA methylation mediates the association of male age on reproductive outcomes among couples undergoing infertility treatment.

Sci Rep · 2021 · PMC7864951 · PMID 33547328

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borderline significantno p-value reported

Altered methylation was also observed in glutamate ionotropic receptor NMDA type subunit 1 ( GRIN1 ; rho = − 0.28, p = 0.059) and synaptic Ras GTPase activating protein 1 ( SNYGAP1 ; rho = 0.26, p = 0.079), although borderline significant with spearman correlations (Fig. 5 B).

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