Molecular imaging of the kinetics of hyperactivated ERK1/2-mediated autophagy during acquirement of chemoresistance.

Cell Death Dis · 2021 · PMC7870816 · PMID 33558461

Europe PMC DOI

hedged sentence

0.0015

closest p · 0.0× alpha

0.0015

boldest claim

The sentences

highly significantp = 0.0015actually significant

However, when the modulation in luminescence signals of the combinatorial groups (CisPac with Trametinib or CQ) were compared among days and with other groups by two-way ANOVA analysis, highly significant differences ( p = 0.0015 and 0.02, respectively) were observed indicating such combinatorial treatments are sufficient to arrest autophagy in short duration.

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