Accuracy of angiopoietin-2 for predicting organ failure in patients with acute pancreatitis: a systematic review and meta-analysis.

1 , 2 The annual incidence of AP ranges from 13 to 45 per 100,000 people, with an increasing trend. 3 – 5 The total mortality rate of AP is 5% to 10%. 4 – 6 The most serious systematic complication of AP is organ failure (OF), including mainly respiratory, circulatory, and renal failure, which are the main causes of death in severe acute pancreatitis (SAP). 6 , 7 Studies have shown that early assessment of OF in AP and adequate treatment are of the utmost importance in reducing the morbidity and mortality associated with AP. 8 – 10 Several scoring systems have been developed to detect severity of AP.

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