Barely Significant
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Comparing intravenous dexmedetomidine and clonidine in hemodynamic changes and block following spinal anesthesia with ropivacaine in lower limb orthopedic surgery: a randomized clinical trial.

Med Gas Res · 2020 · PMC7871933 · PMID 32189663

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highly significantno p-value reported
Its onset of action shorter than bupivacaine (BUP) then is highly significant in anesthesia. 1 Since no study has so far been reported to compare the effects of these adjuvants for hemodynamic changes and block characteristics in spinal anesthetics with ROP and previous studies are performed with BUP, 7 patients can benefit enormously from pain relief and from stable conditions achieved during anesthesia in the operating room, if an adjuvant can be found with minimal hemodynamic changes and a prolonged duration of postoperative analgesia, given the results of the project.

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