109 However, a decreasing trend in coverage for vaccines against diseases including poliomyelitis, diphtheria, tetanus, and pertussis has been reported during the last decade in Europe. 110 The percentage of European children aged two years old who received three doses of the combined DTP vaccine increased from 96.8% in 2009 to 9
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Control of vaccine preventable diseases in Australian infants: reviewing a decade of experience with DTPa-HBV-IPV/Hib vaccine.
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55 Pertussis remains a concern in Europe as well as in the US, with an increasing trend in notifications and the highest burden in those aged less than one year. 120 , 121 Finally, a review assessing immunogenicity and safety of the DTPa-HBV-IPV/Hib vaccine after eight years of licensure in Europe has confirmed vaccine impact and safety using post-marketing surveillance data. 5 This a