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Study on Dissolution Thermodynamics and Cooling Crystallization of Rifamycin S.

ACS Omega · 2021 · PMC7876849 · PMID 33585754

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an increasing trendno p-value reported
Figure 7 shows that the purity of rifamycin S gradually decreased with the decreasing final crystallization temperature, and it was considered that the solubilities of impurities decreased with the decreasing temperature. The yield of rifamycin S was an increasing trend.

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