Combination of miR‑143 and miR‑506 reduces lung and pancreatic cancer cell growth through the downregulation of cyclin‑dependent kinases.

Targeting two cell cycle transitions, at the G 1 /S and G 2 /M represents a highly significant strategy for LC and PC therapy. miR-based therapeutics have emerged as promising mRNA regulators for cancer treatment, capable to control multiple cell functions ( 33 ).

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