Barely Significant
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Prognostic values of tumoral MMP2 and MMP9 overexpression in breast cancer: a systematic review and meta-analysis.

BMC Cancer · 2021 · PMC7877076 · PMID 33568081

Europe PMCDOI
1
hedged sentence
0.0520
closest p · 1.0× alpha
0.0520
boldest claim

The sentences

almost reached significanceP = 0.052so close (0.05 < p ≤ 0.1)
Subgroup of multivariate analysis adjusting HR for the other confounders (ER, PR, HER2, clinicopathological features) revealed that MMP2 overexpression was associated with unfavorable OS (HR = 1.78, 95%CI 1.32–2.39, P < 0.001) and may be an independent prognostic factor. MMP9 overexpression and survival We found an association between MMP9 overexpression and DFS that almost reached significance (HR = 1.73, 95%CI 0.99–3.01, P = 0.052), whereas subgroup of univariate and multivariate analysis both suggested a shorter DFS ( P = 0.034 and 0.006, respectively).

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