Excessive Formation and Stabilization of Dendritic Spine Clusters in the <i>MECP2</i>-Duplication Syndrome Mouse Model of Autism.

There was a nonsignificant trend toward increased baseline spine elimination rate in MECP2 -duplication mice versus littermate controls across the 8 d of imaging ( Fig. 1 I , J ), although our study was not statistically powered to detect this difference given variability in WT animals (1−β = 0.60 for d1→5; 1−β = 0.64 for d5→9).

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