Our results showed that the stiffness-dependent growth of Piezo1 was observed on PAAm hydrogels with different matrix stiffness 1-10kPa, 13-16kPa, 35-38kPa and 62-68kPa, but Piezo2 doesn’t have an obvious trend with stiffness, indicating that Piezo1 is sensitive to the stimulation of matrix stiffness.
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Matrix stiffness regulates myocardial differentiation of human umbilical cord mesenchymal stem cells.
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