Downregulation of PAICS due to loss of chromosome 4q is associated with poor survival in stage III colorectal cancer.

PLoS One · 2021 · PMC7888640 · PMID 33596246

Europe PMC DOI

hedged sentences

0.0790

closest p · 1.6× alpha

0.0790

boldest claim

The sentences

a nonsignificant trendP = 0.079so close (0.05 < p ≤ 0.1)

We then conducted univariate and multivariate Cox analysis in stage II and III patients, showing that PAICS-Negative tumors had a nonsignificant trend toward poor prognosis, although not statistically independent ( P = 0.079, S2 Table ).

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a decreasing trendno p-value reported

Despite upregulated PAICS levels in tumor compared to those of normal mucosa, we found a decreasing trend of PAICS expression during tumor progression and metastasis.

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