Polygenic Contribution to Low-Density Lipoprotein Cholesterol Levels and Cardiovascular Risk in Monogenic Familial Hypercholesterolemia.

Circ Genom Precis Med · 2020 · PMC7889287 · PMID 33079599

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highly significantno p-value reported

These results suggest that while the 28 SNV polygenic score provides a highly significant association with LDL-C levels, more comprehensive polygenic scores will likely provide improvements in predicting LDL-C levels (Figure I in the Data Supplement ).

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