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Synovial fluid IL-1β appears useful for the diagnosis of chronic periprosthetic joint infection.

J Orthop Surg Res · 2021 · PMC7890801 · PMID 33602312

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a decreasing trendno p-value reported
[ 24 ] reported that the AUC, sensitivity, and specificity of IL-1β were 0.92, 90.3% (95% CI, 74%–98%), and 87% (95% CI, 76%–95%), respectively, with a decreasing trend in IL-1β between first-stage explantation and second-stage reimplantation.

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