12 However, a ‘bias‐adjusted’ meta‐analysis of data from 10 studies estimated a pooled odds ratio for a reduction in sensitization of 0.31 (95% CI, 0.17–0.56), which was highly significant. 13 Therefore, prenatal administration seems to reduce sensitization further, from approximately 1.5%, achieved by administration of postpartum anti‐Rh(D) immunoglobulin, to approximately 0.5%.
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