Use and impact of high intensity treatments in patients with traumatic brain injury across Europe: a CENTER-TBI analysis.

Crit Care · 2021 · PMC7901510 · PMID 33622371

Europe PMC DOI

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may be significantno p-value reported

Interventions used to reduce ICP are typically titrated to balance their clinical effect against their side effects, which may be significant or even life-threatening.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.