We found highly significant overrepresentation of a number of enriched biological functions both for downregulated genes ( Figure 1 A, blue edges), mostly related to RNA splicing ( Figure 1 B, pie chart on the left) and upregulated ones ( Figure 1 B, red edges), which include oxygen carrier activity, blood coagulation, and erythrocyte development ( Figure 1 B, pie chart on the right).
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Gene Expression Analysis of Mevalonate Kinase Deficiency Affected Children Identifies Molecular Signatures Related to Hematopoiesis.
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