Combined cellomics and proteomics analysis reveals shared neuronal morphology and molecular pathway phenotypes for multiple schizophrenia risk genes.

PPI enrichment in this combined protein set was highly significant ( p = 0.001), and the largest PPI network that was identified consisted of SNARE proteins involved in neurotransmitter release and contained five dysregulated proteins (SNAP25, SNAP29, NAPB, STX7, and STXBP5) from all three data sets (Fig. 6b ).

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