Given the high level of heterogeneous GagPol expressed under the strong TEF1 promoter in the context of the high copy number 2-micron-based plasmid, competition for cellular resources between the inherent virus and an additional replication-competent structure might be significant, resulting in the rapid loss of selective pressure-free counterpart LA-1 dsRNA.
← all excerpts
Specificity Determination in <i>Saccharomyces cerevisiae</i> Killer Virus Systems.
1
—
—