By comparing the expression of miRNAs in therapy-sensitive and therapy-resistant NB patients, only miR-16 was significantly down-regulated in the bone marrow of non-responder patients ( Figure 3 ), while the other miRNAs analyzed were not significantly modified, even though a slight trend of reduction in non-responder patients was observed.
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Potential Role of miRNAs in the Acquisition of Chemoresistance in Neuroblastoma.
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