Cerebrospinal Fluid Biomarkers of Alzheimer's Disease: Current Evidence and Future Perspectives.

The variant rs75932628 confers a substantially higher risk of late-onset Alzheimer’s disease, and, in one study, the odds ratio was 2.9 [ 150 ] ( Table 2 ); in another study, which comprised 1887 patients with Alzheimer’s disease, a strong, highly significant association (OR: 5.05, 95% CI: 2.77–9.16; p < 0.001) was observed [ 151 ] ( Table 2 ).

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