The Impact of AC and AC-T Chemotherapy's Toxicities on Quality of Life Among Women with Breast Cancer in Ethiopia: A Prospective Patient-Reported Outcomes Study.

Also, constipation is has a highly significant effect on a patient’s well-being. 72 Likely, in our case, grade≥2 peripheral neuropathy and constipation (4.819≤B≤26.451, P≤0.039) were also the other toxicities of AC and AC-T breast cancer chemotherapy that frequently associated with deterioration of symptom scales/items like fatigue, pain, dyspnea, constipation, diarrhea and/or systemic therapy side effects than their lower-grade counterparts.

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