In some cases, the putative cold adaptation-related transcripts were characterized by extremely significant fold change values, being expressed at several dozen times higher levels in Antarctic species, thereby emerging as the most interesting candidates for in-depth studies.
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Cold Adaptation in Antarctic Notothenioids: Comparative Transcriptomics Reveals Novel Insights in the Peculiar Role of Gills and Highlights Signatures of Cobalamin Deficiency.
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We also need to stress out that many genes showing significant q -values, but moderate consistency score may be involved into cold tolerance as well, although not specifically in the gill tissue, or may be otherwise subject to highly significant inter-specific variations of expression levels.