An extensive crosstalk occurs between the mediators of oxidative stress and unfolded-protein stress; protein-kinase-like ER kinase (Perk), activating transcription factor-6 (Atf6) transducers in the regulation of VEGF expression, which is highly significant in CNV formation and eliciting AMD-related pathological changes [ 84 , 88 , 120 , 121 ].
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Exacerbation of AMD Phenotype in Lasered CNV Murine Model by Dysbiotic Oral Pathogens.
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