Association among age, gender, menopausal status and small dense low-density lipoprotein cholesterol: a cross-sectional study.

12 13 Another study showed Asian age-related trends of traditional lipid profiles displayed roughly an increasing trend, followed by a decreasing one at the middle-aged stage. 14 15 Meanwhile, sdLDL-C has been regulated by more complex mechanisms than regulating traditional lipids and might be plateaued or increased even at the middle aged by changed metabolic functions with ageing influencing sdLDL-C synthesis. 5 7 12 16 17 Furthermore, the detailed multiple mechanisms of metabolising sdLDLs are unknown in the real-world, population-based setting and the age-related trend of sdLDL-C might be different from the sdLDL-C/LDL-C ratio.

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