Accordingly, we observed a highly significant reduction in the total distance traveled as well as in the average velocity and vertical activity (supported rearing) in vehicle-treated R6/1 animals compared to vehicle-treated wild type littermates indicating a hypoactive phenotype in HD animals ( Figure 1C and Supplementary Image S1B ).
← all excerpts
The Effects of Selective Inhibition of Histone Deacetylase 1 and 3 in Huntington's Disease Mice.
1
—
—