Mutation patterns in recurrent and/or metastatic oropharyngeal squamous cell carcinomas in relation to human papillomavirus status.

Cancer Med · 2021 · PMC7926014 · PMID 33527763

Europe PMC DOI

hedged sentences

0.0700

closest p · 1.4× alpha

0.0790

boldest claim

The sentences

trending toward significancep = 0.070so close (0.05 < p ≤ 0.1)

Significantly different mutation frequencies between all four subgroups were found in TP53 ( p ≤ 0.001), RB1 ( p = 0.024), HRAS ( p = 0.043), and FAT1 ( p = 0.040), and trending toward significance were PIK3R1 ( p = 0.070), TP63 ( p = 0.060), and NOTCH1 ( p = 0.085) (Figure 3 ).

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a trend toward significancep = 0.079so close (0.05 < p ≤ 0.1)

30 Patients with HPV+OPSCC and LDR received less frequent radiotherapy compared to patients with HPV−OPSCC with LDR with a trend toward significance ( p = 0.079, Mann–Whitney U test; data not shown).

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