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Cigarette Smoking, miR-27b Downregulation, and Peripheral Artery Disease: Insights into the Mechanisms of Smoking Toxicity.

J Clin Med · 2021 · PMC7926909 · PMID 33671744

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Nevertheless, the numerical differences between active smokers and never smokers were close to the margin of statistical significance and are consistent with a culprit effect of active smoking in downregulating miR-27b compared with prior smokers and, likely, never smokers as well.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.