Reassessment of the risk of birth defects due to Zika virus in Guadeloupe, 2016.

One 2004 study from centres across France, including Guadeloupe and Martinique, found an overall TOPFA incidence at any gestational age of 0.7%.[ 26 ] In 2005 in Paris, the incidence of TOPFA after 26 weeks gestation was estimated as 0.2%.[ 27 ] The Pan American Health Organization reported the incidence of stillbirth among women in Guadeloupe (2001–2003) to be 1.6%, with a decreasing trend.[ 28 ] The French Pregnancy Cohort found an incidence of 18.6% and 0.7% for miscarriage and stillbirth across France (2010–2013), respectively.[ 29 ] Of 249 fetuses/infants in our Zika virus exposed cohort, there were three instances each of stillbirth and TOPFA (each 1.2% (95%CI: 0.3–3.5), as well as two miscarriages (0.8% (95%CI: 0.1–2.9).

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