Tolerability and Optimal Therapeutic Dosage of Clomipramine for Premature Ejaculation: A Systematic Review and Meta-Analysis.

Sex Med · 2021 · PMC7930847 · PMID 33291044

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a slight trendno p-value reported

16 , 31 However, we observed a slight trend of higher success rates among patients receiving clomipramine than among those receiving the placebo. 4 of 14 studies reported satisfaction data, which revealed a significantly higher satisfaction rate for clomipramine than for the placebo (SMD: 0.40, 95% CI: 0.09–0.70, P < .05; Table 2 ). 32 , 34 , 35 , 37 However, high heterogeneity ( I 2 = 73%) was observed for this outcome.

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