Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition.

Cell · 2021 · PMC7933824 · PMID 33508232

Europe PMC DOI

hedged sentence

0.0530

closest p · 1.1× alpha

0.0530

boldest claim

The sentences

marginally nonsignificantp = 0.053so close (0.05 < p ≤ 0.1)

HLA B44 supertype was found to be marginally nonsignificant (OR = 1.17 [1.00–1.37], p = 0.053), and sex was found to have a significant association (OR = 1.22 [1.03–1.43, p = 1.9 × 10 −2 ), with male patients experiencing better response rates as previously described ( Conforti et al., 2018 ).

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