Vincristine-induced peripheral neuropathy is driven by canonical NLRP3 activation and IL-1β release.

J Exp Med · 2021 · PMC7933984 · PMID 33656514

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a nonsignificant trendno p-value reported

In contrast, Na V 1.9 −/− animals were not protected from vincristine-induced gait disturbances, although there was a nonsignificant trend toward increased paw print areas on days 4 and 7 ( Fig. 6 F and Table S9 ).

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