eQTLs that were shared across multiple scRNA-seq fibroblast cell types showed a highly significant difference compared with eQTLs that were significant in just one fibroblast type ( p < 5 × 10 −324 for eGenes and p = 6× 10 −150 for eSNPs; Fig. 2 a and Additional file 1 : Figure S6A).
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Single cell eQTL analysis identifies cell type-specific genetic control of gene expression in fibroblasts and reprogrammed induced pluripotent stem cells.
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