In line with our expectation based on the literature, we found a highly significant correlation with [18F] THK5351 values within most of the medial temporal lobe (MTL; P value corrected for family-wise error [ P FWE-corrected ] < 0.001; Figure 3A and Table 3 ).
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Early brainstem [18F]THK5351 uptake is linked to cortical hyperexcitability in healthy aging.
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