highly significantp < 0.0001
Although there was a highly significant increase following the 6h of SD in all three groups (2xANOVA: WT: Interaction F 8,137 = 23.2, p < 0.0001; Time: F 8,137 = 12.1, p < 0.0001; SD: F 1,137 = 27.6, p < 0.0001; Tau : Interaction F 8,91 = 5.5, p < 0.0001; Time: F 8,91 = 3.2, p < 0.005; SD: F 1,91 = 46.7, p < 0.0001; Chimera: Interaction F 8,85 = 9.6 p < 0.0001; Time: F 8,85 = 5.2, p < 0.0001; SD: F 1,85 = 6.5, p < 0.05), direct comparison revealed the slower recovery, as reported by delta power during NREMS, in un-entrained Tau mice ( Figure 5M ).