Safety, pharmacodynamic, and pharmacokinetic characterization of vericiguat: results from six phase I studies in healthy subjects.

Eur J Clin Pharmacol · 2021 · PMC7935833 · PMID 33125516

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a slight trendno p-value reported

Exploratory testing for dose proportionality in SD1 demonstrated close to linear PK for AUC and a slight trend towards decreasing C max with increasing doses.

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