Glucagon blockade restores functional β-cell mass in type 1 diabetic mice and enhances function of human islets.

Proc Natl Acad Sci U S A · 2021 · PMC7936318 · PMID 33619103

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a nonsignificant trendno p-value reported

5 H ), while there was a nonsignificant trend toward increased β-cell proliferation in nondiabetic animals.

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a mild trendno p-value reported

Secretion of human insulin showed a mild trend toward an enhanced stimulation in response to glucose/arginine as compared with IgG control-treated mice ( Fig. 5 F ).

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