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Current Challenges in the Management of Infective Endocarditis.

Front Med (Lausanne) · 2021 · PMC7937698 · PMID 33693021

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an increasing trendno p-value reported
In this regard, controversy remains about the true impact of restricting antibiotic prophylaxis in high-risk patients, as recommended by NICE guidelines ( 8 ), with some investigations showing an increasing trend of infective endocarditis afterwards.

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