Altered Regional Cerebral Blood Flow and Brain Function Across the Alzheimer's Disease Spectrum: A Potential Biomarker.

Interestingly, the FC strength between LPCUN and the altered regions of the brain in the AD group showed an increasing trend compared to the SCD and MCI groups.

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Notably, several studies consistently reported that rCBF displayed a decreasing trend with the progression of cognitive impairment in ADS (Binnewijzend et al., 2013 ; Ding et al., 2014 ; Trebeschi et al., 2016 ; Ma et al., 2017 ; Li et al., 2020 ).

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